Table 1.
Patients demographic, clinical and laboratory characteristics.
| Totaln=100 | Intervention group(High flow) n=51 | Control group(Standard O2) n=49 | P | |
|---|---|---|---|---|
| Age, years (min-max) | 58.5 (18-86) | 58 (18-86) | 59 (27-81) | 0.586* |
| Gender, n (%) | 0.780** | |||
| Male | 66(66) | 33(65) | 33(67) | |
| Female | 34(34) | 18(35) | 16(33) | |
| Hematologic disease, n (%) | 0.186** | |||
| AML | 43(43) | 24(47) | 19(39) | |
| Lymphoma | 26(26) | 13(25) | 13(26) | |
| Multiple Myeloma | 19(19) | 6(12) | 13(26) | |
| MDS | 6(6) | 5(10) | 1(2) | |
| ALL | 4(4) | 1(2) | 3(7) | |
| KLL | 1(1) | 1(2) | 0(0) | |
| KML | 1(1) | 1(2) | 0(0) | |
| Reason for acute respiratory failure, n (%) | ||||
| Pneumonia | 74(74) | 40(78) | 34(70) | 0.424** |
| Extra pulmonary Sepsis | 10(10) | 6(12) | 4(8) | |
| Pleural effusion | 7(7) | 3(6) | 4(8) | |
| Non-infections pulmonary disease | 4(4) | 0(0) | 4(8) | |
| CHF | 2(2) | 1(2) | 1(2) | |
| ARDS | 1(1) | 0(0) | 1(2) | |
| Other | 2(2) | 1(2) | 1(2) | |
| APACHE II score,median (min-max) | 17 (5-29) | 18 (5-25) | 16 (7-29) | 0.014* |
| SOFA score, median (min-max) | 6 (0-10) | 6 (2-10) | 5 (0-10 | 0.112* |
| GCS, median (min-max) | 15 (12-15) | 15 (13-15) | 15(12-15) | 0.715* |
| CCI, median (min-max) | 3 (1-10) | 3 (2-9) | 3 (1-10) | 0.282* |
| PaO2/FiO2 ratio, median (min-max) | 262 (190-295) | 257 (209-295) | 276 (190-295) | 0.073* |
| pH, median (min-max) | 7.48 (7.31-7.59) | 7.48 (7.31-7.59) | 7.49 (7.36-7.59) | 0.178* |
| PO2, median (min-max) | 55.1 (40-62) | 53.4 (44-62) | 58 (40-62) | 0.062* |
| PCO2, median (min-max) | 30 (17-41) | 30 (17-41) | 32.5 (19-41) | 0.444* |
| HCO3, median (min-max) | 23 (11.6-31.6) | 23.3 (13.9-30.6) | 23 (11.6-31.6) | 0.646* |
| Lactate, mmol/L median (min-max) | 1.43 (0.57-8.40) | 1.50(0.6-4.8) | 1.40(0.57-8.4) | 0.497* |
| Hemoglobin concentration, median (min-max) | 8.45 (4.5-13.6) | 8.2 (4.5-11.3) | 8.7 (6.3-13.6) | 0.030* |
| White blood cell count/μL, median (min-max) | 4985 (0.0-169300) | 5580 (0.0-169300) | 4060 (0.0-93390) | 0.409* |
| Platelet count/μL median (min-max) | 34000 (4000-385000) | 33000(6000-290000) | 35000 (4000-385000) | 0.581* |
AML: acute myelomonocytic leukemia, MDS: myelodysplastic syndrome, ALL: acute lymphocytic leukemia, CLL: Chronic lymphocytic leukemia, CML: chronic myelomonocytic leukemia, CCI: Charlson comorbidity index.*Comparisons between groups were performed using the Mann–Whitney U test. **Comparisons between groups were performed using the chi-square test.