Table 2.

The evaluation of risk factors related to intubation and mortality with regression analyses (n = 382).

	Risk factors related to intubation				Risk factors related to mortality
	Univariate logistic regression (LR) analysis		Multivariate LR model		Univariate COX regression(CR) analysis		Multivariate CR model
	Crude OR (95%CI)	P	Adjusted OR (95% CI)	P	Crude HR (95% CI)	P	Adjusted HR (95% CI)	P
Sex (ref: male)	1.114 (0.665–1.865)	0.682	3.022 (1.183–7.719)	0.021	1.418 (0.882–2.281)	0.150	1.533 (0.802)	0.196
Age	1.056 (1.039–1.074)	<0.001	1.039 (1.014–1.065)	0.002	1.043 (1.028–1.059)	<0.001	1.047 (1.026–1.068)	<0.001
Current smoking* (ref: no)	4.723 (2.784–8.011)	<0.001	9.364 (3.769–23.267)	<0.001	2.011 (1.231–3.284)	0.005	2.590 (1.334–5.025)	0.005
Hypertension(ref: no)	6.633 (3.681–11.953)	<0.001	0.497 (0.156–1.584)	0.237	3.187 (1.859–5.464)	<0.001	0.937 (0.400–2.192)	0.880
Diabetes mellitus (ref: no)	2.696 (1.492–4.873)	0.001	0.785 (0.351–1.756)	0.556	2.107 (1.250–3.551)	0.005	1.271 (0.719–2.246)	0.409
ACE inh or ARB use(ref: no use)	8.992 (4.963–16.293)	<0.001	5.363 (1.870–15.382)	0.002	2.566 (1.529–4.305)	<0.001	0.937 (0.433–2.028)	0.870
PPI therapy, ≥4 weeks PPI use(ref: no use)	5.149 (3.001–8.833)	<0.001	4.532 (2.233–9.200)	<0.001	1.944 (1.188–3.182)	0.008	1.83 (1.065–2.419)	0.031

PPI: proton pump inhibitor; ACE inh: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; OR: odds ratio; HR: hazard ratio; CI: confidence interval.