Figure 1. Cytotoxic and cytostatic effects related to saponin content of WYE in MDA-MB-231 cells. The data represent the mean±S.E.M, n=4 for cell viability (at 24 h), cell proliferation (at 6 days) plotted as % (untreated) controls and WYE saponin foam (where 592 μg/ml was set at 100% control), n=3. Significant differences between the controls and treatment groups were determined by a one way ANOVA, followed by a Tukey post hoc test ,*p<0.05. The gene chip icons, represent the 2 concentrations at which microarray analysis work was conducted representing WYE sublethal Low (15 μg/ml) and WYE sub-lethal High (30 μg/ml).
