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. 2021 Oct 22;12:718002. doi: 10.3389/fphys.2021.718002

FIGURE 4.

FIGURE 4

Docking models of L-PGDS complexes with PGH2 based on X-ray crystallography (Kumasaka et al., 2009). Amino acid residues important for interaction with PGH2 are shown in panel (A). R85, K92, F83, S82, C65, S45, T67, Y149, and T147 are shown in stick-model form in panel (B). Hydrogen bonding network around Cys65 and 15-hydroxy group of PGH2 are also indicated in panel (B).