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. 2021 Oct 22;11:751777. doi: 10.3389/fonc.2021.751777

Table 2.

Univariable and multivariable analysis of OS in the VR group.

Variables Univariable analysis Multivariable analysis
P value HR (95% CI) P value
Age, y (≤60/>60) 0.971
Sex (Male/Female) 0.667
Cirrhosis (yes/no) 0.060
Ascites (yes/no) 0.144
Splenomegaly (yes/no) 0.007 1.340 (1.095-1.641) 0.005
ICGR 15 (≤10%/>10%) 0.751
Tumor capsule (yes/no) 0.151
Up-to-seven criteria
(beyond/within)
0.002 1.298 (1.048-1.607) 0.017
AFP, ug/L (≤20/>20) 0.030
GGT, u/L (≤50/>50) 0.956
AST, u/L (≤40/>40) 0.700
ALT, u/L (≤40/>40) 0.511
Albumin, g/L (≤30/>30) 0.158
TBIL, umol/L (>20.5/≤20.5) 0.049 1.505 (1.104-2.052) 0.010
PT, sec (≤14/>14) 0.431
WBC, 109/L (≤4/>4) 0.771
HB, g/L (≤120/>120) 0.626
Platelet count, 109/L (≤100/>100) 0.019 1.326 (1.088-1.617) 0.005
Sorafenib after TACE (yes/no) <0.001 0.605 (0.494-0.742) <0.001
Radical therapy after TACE (yes/no) 0.606

CI, confidence interval; HR, hazard ratio; OS, overall survival.