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. 2021 Aug 16;83(10):1500–1508. doi: 10.1292/jvms.21-0298

Table 2. Experimental design for the primary immunization of mice.

Group No. of mice/group Antigen Dosage/vol Adjuvant Route
Negative control 10 Phosphate-buffered saline (PBS) 100 μl Freund’s complete Subcutaneous
Inactivated group 10 Inactivated straina 4.0 × 109 CFU/100 μl Freund’s complete Subcutaneous
Recombinant protein LpxC 10 LpxC 100 μg/100 μl Freund’s complete Subcutaneous
Recombinant protein GmhA 10 GmhA 100 μg/100 μl Freund’s complete Subcutaneous
LpxC+ GmhA mixed protein 10 LpxC+ GmhA 100 μg/100 μlb Freund’s complete Subcutaneous

a CY1201 strain (Serotype 13) inactivated with formaldehyde. b The mice from LpxC+GmhA mixed protein were immunized with 50 μg of LpxC and 50 μg of GmhA.