Table 3. Secondary attack rate of SARS-CoV-2 infection by vaccination status of the index case (≥ 12 years) and vaccine effectiveness against transmission, the Netherlands, August–September 2021 (n = 4,921 index cases).
Analysis | Unvaccinated index | Partly vaccinated index | Fully vaccinated index | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SAR | SAR | Crude VET | Adjusted VETa | SAR | Crude VET | Adjusted VETa | |||||||
Positive | Total | % | Positive | Total | % | % (95% CI) | % (95% CI) | Positive | Total | % | % (95% CI) | % (95% CI) | |
Unvaccinated household contacts | 547 | 2,517 | 22 | 21 | 121 | 17 | 28 (−18 to 56) |
38 (−2 to 62) |
38 | 303 | 13 | 50 (28 to 65) |
63 (46 to 75) |
Fully vaccinated household contacts | 164 | 1,505 | 11 | 37 | 614 | 6 | 46 (22 to 63) |
46 (20 to 63) |
256 | 2,070 | 12 | −16 (−44 to 6) |
40 (20 to 54) |
CI: confidence interval; SAR: secondary attack rate; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2, VET: vaccine effectiveness against transmission.
a Adjusted for age group of the index case and contact and for week of notification of the index case.