Table 3.
Multivariable regression analyses of factors associated with general practitioner contact during follow-up among prostate cancer survivors (N = 475)
| Multivariable association | |||
|---|---|---|---|
| Block A (n = 458) | Block B (n = 409) | Block C (n = 409) | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Patient and treatment characteristics | |||
| Age at time of questionnaire | 1.0 (0.9:1.0) | 1.0 (0.9:1.1) | 1.0 (0.9:1.1) |
| Education level | |||
| Low | 1 (ref) | 1 (ref) | 1 (ref) |
| Intermediate | 1.3 (0.8:2.0) | 1.3 (0.8:2.2) | 2.0 (1.1:3.4)* |
| High | 1.1 (0.7:1.8) | 1.1 (0.7:1.9) | 1.7 (0.9:3.1) |
| Marital Status | |||
| No partner | 1 (ref) | 1 (ref) | 1 (ref) |
| Partner | 1.5 (0.8:2.8) | 1.3 (0.7:2.6) | 2.0 (0.9:4.2) |
| Number of comorbidities | |||
| No comorbidities | 1 (ref) | 1 (ref) | 1 (ref) |
| 1 comorbidity | 1.0 (0.6:1.6) | 1.0 (0.6:1.6) | 0.9 (0.5:1.6) |
| ≥ 2 comorbidities | 1.2 (0.7:1.9) | 1.0 (0.5:1.7) | 0.9 (0.5:1.8) |
| Primary treatment | |||
| Active surveillance | 1 (ref) | 1 (ref) | 1 (ref) |
| Surgery | 2.7 (1.5:4.9)*** | 2.9 (1.5:5.5)*** | 2.8 (1.4:6.0)** |
| Radiotherapy | 1.6 (0.8:3.3) | 1.7 (0.8:3.7) | 1.6 (0.7:3.7) |
| Hormonal therapy | 3.1 (1.4:6.8)** | 3.1 (1.3:7.4)** | 3.5 (1.3:9.5)* |
| Radiotherapy and hormonal therapy | 1.7 (0.9:3.2) | 1.6 (0.7:3.4) | 1.6 (0.7:3.8) |
| Watchful waiting | 1.8 (0.5:7.6) | 2.8 (0.6:12.9) | 2.7 (0.5:14.2) |
| Other/unknown | 0.4 (0.1:1.3) | 0.3 (0.1:1.3) | 0.2 (0.1:1.0) |
| Time since diagnosis in years | 1.0 (0.9:1.2) | 1.1 (0.9:1.2) | 1.1 (0.9:1.2) |
| Symptoms (per 10 units) | |||
| Urinary symptoms | – | 1.0 (0.9:1.2) | 0.9 (0.8:1.1) |
| Bowel symptoms | – | 1.2 (1.0:1.5) | 1.4 (1.1:1.9)* |
| Hormonal symptoms | – | 1.3 (1.0:1.6)* | 1.4 (1.1:1.9)** |
| Sexual activity | – | 0.9 (0.9:1.0) | 0.9 (0.8:1.0) |
| Incontinence aida (n = 139) | – | 1.3 (1.1:1.6)** | 1.6 (1.2:2.1)*** |
| Sexual functioninga (n = 223) | – | 1.0 (0.9:1.2) | 1.1 (0.9:1.2) |
| Patients’ evaluation of their GP | |||
| Satisfaction with GP | – | – | 9.5 (5.2:17.2)*** |
| Trust in GP | – | – | 1.3 (0.4:3.9) |
| Knowledge of GP | – | – | 1.4 (0.5:4.6) |
Note: reference category for symptoms = having no symptoms or being not active/functioning; reference category for patients’ evaluation of their GP = being not satisfied with GP, having no trust in GP, and low appraised knowledge of GP
aBlock B and C were analyzed without the conditional items concerning ‘incontinence aid’ and ‘sexual functioning’. Sub-analyses were performed for patients who completed the question regarding incontinence aid and the questions regarding sexual functioning. The effects of the variables in the sub-analyses were corresponding with the regular analyses (for some variables the significance changed slightly, but this was probably due to under power)
Abbreviations: OR Odds Ratio, CI Confidence interval, GP General Practitioner, ref reference category, -- not applicable; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001