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. 2021 Oct 22;9:756743. doi: 10.3389/fcell.2021.756743

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Copyright © 2021 Qiang, Shen, Noman, Guo, Jin, Lin, Pan, Lu, Li and Gong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fibroblast growth factor 21 reduces oxidative stress after liver injury. Samples were collected at 0, 24, and 48 hpa to assess oxidative stress in the damaged liver. (A) Evaluation of SOD activity in the control and differentially treated embryos. (B) Evaluation of CAT activity in the control and differentially treated embryos. (C) Evaluation of MDA content in the control and differentially treated embryos. (D) Evaluation of AST activity in the control and differentially treated embryos. (E) Evaluation of ALT activity in the control and differentially treated embryos. DMSO group: without Mtz treatment, DMSO was applied. Mtz group: after Mtz treatment, grow naturally. Mtz+FGF21 group: after Mtz treatment, treated with FGF21 standard protein. Significance: *p< 0.05, **p< 0.01, and ***p< 0.001 vs. DMSO group. Data are expressed as mean ± SEM (n = 40 per group, repeat 3 times for each test).