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. 2021 Nov 2;9:e12303. doi: 10.7717/peerj.12303

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©2021 Subkorn et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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Leukemic cells were treated with IC₅₀ of punicalagin for 48 h. The mRNA expression of (A) caspase family genes, (B) Bcl-2 family as well as (C) ULK1 and mTOR were determined using reverse transcription-quantitative PCR. *p < 0.05 was considered to be a statistically significant difference from the control group.