TABLE 4.

Specialized investigations for complex or refractory cases

INVESTIGATION	BENEFITS	LIMITATIONS/ DISADVANTAGES
MAGNETIC RESONANCE IMAGING	Considered by some the best diagnostic tool, especially after IV contrast media55 Provides anatomical reference	Cost Limited benefit in product identification76
SCINTIGRAPHY	Most accurate in diagnosing infection8	Cost Radiation
CT / SPECT	Identification of calcifications	Non-specific findings False positive diagnosis of malignancy76
INFRARED SPECTROSCOPY	Definitive filler identification Absorption spectrum of a filler is comparable to a fingerprint79	Invasive