Table 1.
The Baseline Patient Characteristics Among Four Institutions
| Characteristics | Overall (n=231) | Institution A (n=71) | Institution B (n=74) | Institution C (n=45) | Institution D (n=41) | P |
|---|---|---|---|---|---|---|
| Age (years) | 56.2±11.6 | 58.8±11.5 | 55.3±11.0 | 54.0±11.0 | 55.7±14.8 | 0.083 |
| Sex (%) | 0.024 | |||||
| Male | 205 (88.7%) | 65 (91.5%) | 59 (79.7%) | 41 (91.1%) | 40 (97.6%) | |
| Female | 26 (11.3%) | 6 (8.5%) | 15 (20.3%) | 4 (7.9%) | 1 (2.4%) | |
| Number of tumors (%) | <0.001 | |||||
| Single | 113 (48.9%) | 36 (50.7%) | 32 (43.2%) | 26 (57.8%) | 19 (46.3%) | |
| Multiple | 118 (51.1%) | 35 (49.3%) | 42 (56.8%) | 19 (42.2%) | 22 (53.7%) | |
| Albumin (g/L, median with IQR) | 56.2±11.6 | 36.5±4.6 | 38.8±5.3 | 39.7±4.3 | 38.5±6.0 | 0.169 |
| Total bilirubin (umol/L, median with IQR) | 15.3 (11.6) | 15.6 (13.4) | 15.9 (8.0) | 14.9 (7.5) | 15.5 (13.4) | 0.830 |
| Platelet (×109, median with IQR) | 155.0 (103.0) | 143.0 (107.0) | 155.0 (108.75) | 176.0 (106.5) | 140.0 (120.0) | 0.051 |
| Child-Pugh class (%) | 0.088 | |||||
| A | 214 (92.6%) | 66 (93.0%) | 67 (90.5%) | 45 (100%) | 36 (87.8%) | |
| B | 17 (7.4%) | 5 (7.0%) | 7 (9.5%) | 0 | 5 (12.2%) | |
| Etiologies of cirrhosis (%) | 0.038 | |||||
| None | 27 (11.7%) | 12 (16.9%) | 5 (6.8%) | 1 (2.2%) | 9 (22.0%) | |
| HBV | 188 (81.4%) | 54 (76.1%) | 64 (86.5%) | 41 (91.1%) | 29 (70.7%) | |
| HCV | 7 (3.0%) | 3 (4.2%) | 2 (2.7%) | 0 | 2 (4.9%) | |
| Alcohol | 3 (1.3%) | 0 | 2 (2.7%) | 1 (2.2%) | 0 | |
| Cryptogenic | 6 (2.6%) | 2 (2.8%) | 1 (1.4%) | 3 (1.3%) | 1 (2.4%) | |
| Tumor distribution (%) | 0.584 | |||||
| Unilobar | 148 (64.1%) | 43 (60.6%) | 52 (70.3%) | 27 (60.0%) | 26 (63.4%) | |
| Bilobar | 83 (35.9%) | 28 (39.4%) | 22 (29.7%) | 18 (40.0%) | 15 (36.6%) | |
| AFP (%) | 0.134 | |||||
| ≤400 ng/mL | 142 (61.5%) | 40 (56.3%) | 52 (70.3%) | 23 (51.1%) | 27 (65.9%) | |
| >400 ng/mL | 89 (38.5%) | 31 (43.7%) | 22 (29.7%) | 22 (48.9%) | 14 (34.1%) | |
| The largest tumor size (mm, median with IQR) | 75.0 (48.8) | 74.0 (56.0) | 63.0 (41.5) | 102.0 (67.1) | 84.9 (43.6) | <0.001 |
Abbreviations: IQR, inter-quartile range; AFP, alpha fetoprotein.