Table 2.

Summary of combination strategies against severe COVID-19 (Ky and Mann, 2020; Lythgoe and Middleton, 2020).

Treatment strategies	Drug name	Mechanism of action
Antiviral/Antimalarial	Lopinavir, ritonavir, hydroxychloroquine	Viral replication and viral entry
	Remdesivir, hydroxychloroquine remdesivir; hydroxychloroquine	Viral replication and viral entry
	oseltamivir, chloroquine,
	Darunavir, ritonavir, lopinavir, oseltamivir, favipiravir	Viral replication and viral entry
Antiviral/immunomodulators	Lopinavir þ ritonavir; ribavirin; IFN-b1b	Antiretroviral and immunomodulatory
	Favipiravir þ tocilizumab	Antiretroviral and immunomodulatory
Antiviral/Antimalarial/immunomodulators	Remdesivir; lopinavir þ ritonavir; IFN-b1a; hydroxychloroquine	Antiretroviral, viral entry, and immunomodulatory