Table 1.

Factors that influence QOL in people living with IBD

	Impact on QOL		Mechanism of influence on QOL
	Children	Adults
IBD disease activity	Negative	Negative	• Self-esteem • Relationships • Hygiene • Security • Depressive symptoms • Social isolation • Psychologic distress
Psychologic distress	Negative	Negative	• Reduced energy • Impaired body image • Maladaptive coping mechanisms • Social isolation
Psychologic interventions	Positive	Positive	• Reduction of exacerbating factors related to increased disease-related psychologic distress
Surgery	Negative	Negative	• Fear of complications • Need for an ostomy • Body image • More severe form of disease
Pain	Negative	Unknown	• Disability • Depressive symptoms • Disease-related psychologic distress
Parental stress	Negative	Unknown	• Perceived difficulty of medical stressors
Effective medical therapy	Positive	Positive	• Induction of long-term remission
Health information gathering from internet	Negative	Negative	• Reduced certainty
Poor sleep quality	Negative	Negative	• Fatigue • Daytime dysfunction

IBD, Inflammatory bowel disease; QOL, Quality of life.