Table 4.
Entry | R2 | σa | νa | ΔG°rd (kcal/mol)b |
---|---|---|---|---|
1 | t-Bu, 2h | –0.20 | 1.24 | -23.1 |
2 | Me, 2i | –0.17 | 0.52 | -11.4 |
3 | Ph, 2j | –0.01 | 0.57 | -5.1 |
4 | H, 2k | 0.00 | 0.00 | 1.2 |
5 | Cl, 2l | 0.23 | 0.55 | -8.0 |
6 | CF3, 2m | 0.54 | 0.91 | -9.0 |
Hammett sigma para (σp) and Charton steric (ν) parameters3 for the R groups.
Values are obtained using UM06/6–311+G(d,p),SMD: 1,4-dioxane // UB3LYP/6–31G(d).