. Author manuscript; available in PMC: 2022 May 1.

Published in final edited form as: Med Chem Res. 2021 Apr 9;30(5):1166–1174. doi: 10.1007/s00044-021-02720-x

Table 2.

Activity profiles of the screened compounds. Data are shown as enzyme inhibition (IC₅₀) values in μM.

	Compound ID	MAO-A	MAO-B	AChE	BSA
1	F0012-0121	1.74	40.12	ia	12.66
2	F0536-0298	ia	19.71	ia	>100
3	F0647-0340	ia	ia	ia	95.12
4	F0647-0350	ia	0.55	ia	38.54
5	F2609-0119	ia	ia	ia	40.1
6	F2616-0708	ia	0.243	ia	>100
7	F5123-0117	ia	16.38	22.04	>100
8	F5123-0122	ia	5.55	35.28	>100
9	F5313-0560	ia	83.09	ia	>100
10	F5313-0599	ia	96.97	ia	>100
Zonisamide			22.6
Tranylcypromine		3.7
Indomethacin					19.72
Diclofenac					16.05

i.a.: inactive at dose tested.