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. 2021 Nov 5;7(45):eabj3400. doi: 10.1126/sciadv.abj3400

Fig. 2. Depressive- and anxiety-like behaviors.

Fig. 2.

After IS with or without ethanol exposure, the total distance traveled (a) and time spent in the center (b) in the OFT (A) were assessed on the 28th day. After a period of 6 hours, total global activity (a), immobility duration (b), and activity duration (c) in the TST (C) were assessed. The traveled distance (a), total number of entries (b), entries into the open arms (c), and spent time in the open arms (d) in the EPM (B) were assessed on the 29th day. Total global activity (a), immobility duration (b), and latency to immobility (c) in the FST (D) were assessed on the 30th day. The data are expressed as the means ± SD (n = 8). *P < 0.05 and **P < 0.01 compared to the unstressed mice, and #P < 0.05 compared to the mice not exposed to ethanol.