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. 2021 Nov 5;7(45):eabi6442. doi: 10.1126/sciadv.abi6442

Fig. 6. Assessment of severity of colitis following adoptive transfer of DSS-treated microbiota to antibiotic-treated C57BL/6 mice.

Fig. 6.

(A) Schematic of cecal microbiota transfer followed by induction of colitis with 3.5% DSS. Each group had three to four mice. (B) DAI. *P < 0.05 between C57BL/6 mice receiving DKO microbiota and C57BL/6 mice receiving Tph1−/− microbiota. (C) Macroscopic damage score on day 5 after DSS. Colon tissue was collected to determine (D) MPO activity; (E) IL-1β, IL-6, and TNF-α; (F) histological score; and (G) representative micrographs on day 5 after DSS. Scale bars, 100 μm. Data are represented as means ± SEM. *P < 0.05 for graphs (C), (D), (E), and (F).