TABLE 1.

Incidence rates of allergy to hyaluronidase

STUDY	ROUTE	OVERALL INCIDENCE RATE
Szefalusi et al15	Intravenous	31.25%
Leibovitch et al17	Peribulbar	0.13%
Raichura et al18	Peribulbar	0.006% (first exposure)/0.016% second exposure
Zamora-Alejo et al22	Peribulbar	0.05%
Kempeneers et al23	Retrobulbar	0.05%
Eberhart et al24	Peribulbar	0.69%
Escolano et al33	Peribulbar	0.03%