Table 1.
Characteristics of Confirmatory Cohort Based on Presence of Neuropathic Pain
| Variable |
No neuropathic pain (n = 38) |
Neuropathic pain (n = 28) |
Total (n = 66) |
P
|
|---|---|---|---|---|
| Demographics | ||||
| Age (years) [mean ± SD] | 36.62 ± 10.78 | 40.11 ± 12.77 | 38.10 ± 11.70 | 0.86 |
| Male, n (%) | 24 (63.1) | 24 (85.7) | 48 (72.7) | 0.04 |
| Injury characteristics | ||||
|---|---|---|---|---|
| AIS classification |
|
|
|
|
| • A, n (%) |
10 (66.7)a |
20 (71.4) |
30 (69.8) |
0.60 |
| • B, n (%) |
4 (26.7)a |
4 (14.3) |
8 (18.6) |
|
| • C, n (%) |
1 (6.6)a |
4 (14.3) |
5 (11.6) |
|
| Tetraplegia, n (%) |
4 (26.7)a |
6 (21.4) |
10 (23.3) |
0.71 |
| Injury duration (years) [mean ± SD] |
6.67 ± 8.10a |
8.81 ± 9.06 |
8.06 ± 8.70 |
<0.0001 |
| Age at injury (years) [mean ± SD] | 28.73 ± 11.41a | 30.39 ± 12.44e | 29.73 ± 11.91 | 0.003 |
| Medication use | ||||
|---|---|---|---|---|
| Active opioid use, n (%) |
4 (10.5) |
8 (34.8)e |
12 (19.7) |
0.04 |
| Active spasmolytic use, n (%) |
6 (15.8) |
10 (43.5)e |
16 (26.2) |
0.01 |
| Active gabapentin use, n (%) |
3 (7.9) |
10 (43.5)e |
13 (21.3) |
0.002 |
| Active antidepressant use, n (%) | 1 (2.6) | 2 (8.7)e | 3 (4.9) | 0.55 |
| Health habits | ||||
|---|---|---|---|---|
| Current alcohol user, n (%) |
32 (86.5)b |
19 (90.5)f |
51 (87.9) |
1.0 |
| Lifetime alcohol exposure kg/years [mean ± SD] |
147.78 ± 205.11c |
116.27 ± 97.21c |
136.04 ± 172.40 |
0.23 |
| Current smoker, n (%) |
1 (2.7)b |
4 (19.1)f |
5 (8.6) |
0.05 |
| Cigarette exposure (pack-years) [mean ± SD] | 9.67 ± 9.88d | 6.21 ± 5.03d | 7.56 ± 7.24 | 0.005 |
a
Among SCI n = 15; bavailable data for n = 37; camong ever alcohol users; damong ever smokers; eavailable data for n = 23; favailable data for n = 21.
AIS, American Spinal Injury Association Impairment Scale; SCI, spinal cord injury; SD, standard deviation.