Table 1. Complete list of genes that exhibited a greater than twofold change in expression in the F1 progeny of parents exposed to P. vranovensis or osmotic stress in all four species tested.
| Genes that change in F1 progeny of all species exposed to P. vranovensis |
Predicted function |
|---|---|
| C18A11.1 | Unknown |
| R13A1.5 | Unknown |
| D1053.3 | Unknown |
| pmp-5 | ATP-binding activity and ATPase-coupled transmembrane transporter activity, ortholog of human ABCD4 |
| C39E9.8 | Unknown |
| nit-1 | Nitrilase ortholog – predicted to enable hydrolase activity |
| lips-10 | Lipase related |
| srr-6 | Serpentine receptor, class R |
| Y51B9A.6 | Predicted to enable transmembrane transporter activity |
| gst-33 | Glutathione S-transferase |
| ptr-8 | Patched domain containing, ortholog of human PTCHD1, PTCHD3, and PTCHD4 |
| ZC443.1 | Predicted to enable D-threo-aldose 1-dehydrogenase activity |
| cri-2 | Conserved regulator of innate immunity, ortholog of human TIMP2 |
| Y42G9A.3 | Unknown |
| ttr-21 | Transthyretin-related, involved in response to Gram-negative bacteria |
| F45E4.5 | Involved in defense against Gram-negative bacteria |
| C42D4.1 | Domain of unknown function DUF148 |
| asp-14 | Predicted to enable aspartic-type endopeptidase activity. Involved in innate immune response |
| cyp-32B1 | Cytochrome P450 family. Ortholog of human CYP4V2 |
| nas-10 | Predicted to enable metalloendopeptidase activity and zinc ion-binding activity |
| W01F3.2 | Unknown |
| nhr-11 | Nuclear hormone receptor |
| F26G1.2 | Unknown |
| F48E3.2 | Predicted to enable transmembrane transporter activity |
| hpo-26 | Unknown, hypersensitive to pore forming toxin |
| R05H10.1 | Unknown |
| C08E8.4 | Involved in innate immune response |
| C11G10.1 | Unknown |
| Y73F4A.2 | Unknown, DOMON domain containing |
| bigr-1 | Predicted to enable hydrolase activity |
| nlp-33 | Neuropeptide like, involved in innate immune response |
| far-3 | Predicted to enable lipid-binding activity |
| Genes that change in F1 progeny of all species exposed to both osmotic stress and P. vranovensis | |
| C30B5.6 | Unknown |
| hphd-1 | Predicted to enable hydroxyacid–oxoacid transhydrogenase activity. Ortholog of human ADHFE1 |
| C42D4.3 | Unknown, DB module and domain of unknown function DB |
| Genes that change in F1 progeny of all species exposed to osmotic stress | |
| ttr-15 | Transthyretin-like family |
| F08F3.4 | Predicted to enable catalytic activity. Involved in innate immune response.Ortholog of human TDH |