Table 1.

Cases of Anti-Glomerular Basement Membrane Disease Post SARS-CoV2 Infection

	Case 1	Case 2	Case 3	Case 4
Age/Gender	36/F	18/M	52/M	32/F
Comorbidity	Nil	Nil	Hypertensive	Nil
Smoking status	Nil	Nil	Smoker	Nil
Clinical presentation	Lethargy, hematuria, vomiting	Headache, accelerated hypertension	Volume overload, vomiting	Volume overload, fever, hematuria, oliguria
Preceding clinical SARS-CoV2 infection	Present – mild	Present – moderate	Present – mild	Present – moderate
Prodrome duration	4 weeks	8 weeks	6 weeks	4 weeks
Alveolar hemorrhage	Absent	Absent	Absent	Absent
Hemoglobin	7.8 g/dl	11g/dl	8g/dl	8.2g/dl
Renal syndrome	AKI	AKI-RRT	AKI-RRT	AKI-RRT
Platelets	2,30,000/mm3	1,25,000/mm3	1,50,000/mm3	1,12,000/mm3
Serum creatine	3.4mg/dl	7mg/dl	12mg/dl	16mg/dl
C-reactive protein	0.7 mg/L	15 mg/L	4 mg/L	65 mg/L
Anti-GBM titre (IU/mL; normal <6.9)	287	567	323	386
ANCA	Negative	Positive (p-ANCA)	Negative	Negative
Renal Biopsy	Crescentric glomerular Nephritis, no interstitial fibrosis and tubular atrophy, linear IgG staining	Cellular and fibrocellular crescents, linear IgG staining, no interstitial fibrosis and tubular atrophy	Circumferential fibrocellular and cellular crescents, linear IgG staining, IFTA 40%	Cellular and fibrocellular crescents, linear IgG staining, no interstitial fibrosis and tubular atrophy
SARS-CoV2
1. RTPCR	1. Negative	1. Negative	1. Negative	1. Negative
2. IgG antibody	2. Negative	2. Negative	2. Positive	2. Negative
3. IgM antibody	3. Positive	3 .Positive	3. Positive	3. Positive
Treatment	Plasma exchange, steroids	Plasma exchange, steroids, cyclophosphamide	Plasma exchange, steroids, cyclophosphamide	Plasma exchange, steroids, cyclophosphamide
Outcome	Outpatient follow-up	Outpatient follow-up	On weekly twice RRT	Inpatient RRT
Last creatinine	3.8mg/dl	5mg/dl	5.8mg/dl	6.8mg/dl