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. 2021 Jul 2;37(21):3744–3751. doi: 10.1093/bioinformatics/btab491

Table 1.

Showing the Q3 scores and micro-averaged F1 scores achieved by S4PRED, SPIDER3-Single and PSIPRED-Single on two test sets; a test set of de novo designed proteins (labelled ‘Designed’) and a test set of orphan proteins (labelled ‘Orphans’)

Q3
F1
Orphans Designed Orphans Designed
S4PRED 75.3% 90.7% 0.754 0.910
SPIDER3-Single 73.3% 89.4% 0.733 0.890
PSIPRED-Single 71.1% 86.6% 0.718 0.868

Note: Results in bold show the superior performance of S4PRED.