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The effect of sex-linkage on synonymous and nonsynonymous polymorphism. Proportion of nonsynonymous sites among autosomal and X-linked LD-pruned protein-coding loci, for each of 15 MAF bins (MAF bin width = 0.03; points are at MAF bin mid-point), with linear regression lines (±95% CIs) presented for visual emphasis. Regression coefficients from this analysis were used to make inferences about dominance and NeX/NeA (i.e., Figure 6B).
