Figure 6.

BLA PV neurons constrain association formation under variations in prediction error. A, B, PV-Cre rats received BLA infusions of Cre-dependent eNpHR3.0 or eYFP and fiber optic cannulae into the BLA. Viral spread shown is specific to expression within the BLA and does not show occasional spread into adjacent regions. C, eNpHR3.0-Block (n = 8) and eYFP-Block (n = 7) both learned fear to CSA in Stage I, and eYFP-Control (n = 8) learned to fear CSAB during Stage II. Blocking was demonstrated at test. BLA photoinhibition during the Stage II shock US reduced blocking and restored fear learning to CSB in group eNpHR3.0-Block. *p < 0.05.