FIGURE 2.

Factors affecting the brain vasculature and leading to neurological conditions. The brain, which has elevated metabolic needs but poor energy storage, is highly dependent on a continuous supply of nutrients and oxygen from the blood stream, and is thus dependent on the integrity of its vasculature. Vasculature of the brain is the most complex and dense in the human body. Yet, it is maintaining a very fragile equilibrium and is the target of numerous pathological conditions that affect neuronal maturation and function. Figure made using BioRender.