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. 2021 Oct 29;2021:5518750. doi: 10.1155/2021/5518750

Table 2.

The information of target proteins of “MOR” predicted by network pharmacology analyses.

Uniprot no. Protein name Gene name Closeness centrality Degree Betweenness centrality
P41182 B-cell lymphoma 6 protein BCL6 0.2056 8 0.0369
P17535 Transcription factor jun-D JUND 0.1857 4 0.0023
P15941 Mucin-1 MUC1 0.2361 3 0.0339
Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon IKBKE 0.1967 5 0.0052
Q16539 Mitogen-activated protein kinase 14 MAPK14 0.2029 5 0.0022
Q03164 Histone-lysine N-methyltransferase 2A KMT2A 0.1989 5 0.0056
P35968 Vascular endothelial growth factor receptor 2 KDR 0.1856 11 0.0189
Q99558 Mitogen-activated protein kinase kinasekinase 14 MAP3K14 0.1887 13 0.0111
P19838 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.1959 21 0.0189
P04637 Cellular tumor antigen p53 TP53 0.2289 60 0.1438
O15350 Tumor protein p73 TP73 0.1879 9 0.0037
P09874 Poly [ADP-ribose] polymerase 1 PARP1 0.2023 11 0.0449
P60900 Proteasome subunit alpha type-6 PSMA6 0.1846 3 0.0022
Q13546 Receptor-interacting serine/threonine-protein kinase 1 RIPK1 0.1833 7 0.0475
Q86WV6 Stimulator of interferon genes protein STING1 0.1851 8 0.0049
Q04206 Transcription factor p65 RELA 0.1974 19 0.0133
P24385 G1/S-specific cyclin-D1 CCND1 0.2329 10 0.0877
P05412 Transcription factor AP-1 JUN 0.2135 13 0.0278
P25963 NF-kappa-B inhibitor alpha NFKBIA 0.2177 18 0.0477
P06396 Gelsolin GSN 0.2326 5 0.0276
P31749 RAC-alpha serine/threonine-protein kinase AKT1 0.2153 13 0.0323
Q9C000 NACHT, LRR and PYD domains-containing protein 1 NLRP1 0.1853 4 0.0141
Q16665 Hypoxia-inducible factor 1-alpha HIF1A 0.2139 12 0.0151
O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK 0.2166 18 0.0318
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.2158 15 0.0206
Q9Y6K9 NF-kappa-B essential modulator IKBKG 0.2163 23 0.0446