Figure 1.

Effect of PM2.5 exposure on systemic insulin resistance indicators in Wistar rats. Experiments were performed after PM2.5 instillation at different dosages or saline instillation (control) for 8 weeks. Values are shown as the mean ± standard error of 12 rats/group. ^∗p < 0.05, and ^∗∗p < 0.01. (a) Fasting blood glucose (FBG), (b) fasting insulin (FINS), (c) hemoglobin A1c (HbA1c), (d) Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), and (e) intraperitoneal glucose tolerance testing (IPGTT) curves. (f) The area under the curve (AUC_glu).