The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats

. 2021 Oct 29;2021:2821673. doi: 10.1155/2021/2821673

(b) Intraperitoneal glucose tolerance test in rats (IPGTT) ( $\overset{®}{x} \pm s$ )

	Blood glucose (mmol/L)						AUC_glu
	0′	5′	10′	30′	60′	120′	AUC_glu
A	5.2 ± 0.3	6.3 ± 0.4	6.9 ± 0.5	8.6 ± 0.9	7.8 ± 1.0	5.5 ± 0.3	11.1 ± 0.9
B	6.0 ± 0.5	8.4 ± 0.7	9.8 ± 1.1	11.4 ± 0.9	9.8 ± 1.7	7.4 ± 1.6	14.5 ± 1.2^a
C	7.5 ± 1.5^ab	11.2 ± 1.0^ab	12.2 ± 0.7^a	12.7 ± 1.4^a	11.1 ± 2.6^ab	7.1 ± 0.7^a	16.4 ± 0.9^ab
D	8.5 ± 0.7^abc	13.5 ± 3.1^ab	17.1 ± 4.4^abc	17.5 ± 1.8^abc	9.7 ± 1.7^ab	7.8 ± 2.2^a	19.1 ± 1.4^abc
E	9.5 ± 0.5^abc	12.8 ± 2.9^ab	15.4 ± 3.4^ab	19.2 ± 2.0^abc	15.0 ± 2.9^abc	10.3 ± 0.7^abcd	22.8 ± 1.8^abcd
F	24.56	11.78	12.95	43.22	8.21	9.16	60.61
p	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Note: A: control group; B: 0.75 mg/kg PM2.5 group; C: 2.5 mg/kg PM2.5 group; D: 5 mg/kg PM2.5 group; E: 10 mg/kg PM2.5 group; AUC_glu: area under the curve; F: F value; p: p value. Compared to the control group, ^ap < 0.05; compared to the 0.75 mg/kg PM2.5 group, ^bp < 0.05; compared to the 2.5 mg/kg PM2.5 group, ^cp < 0.05; compared to the 5 mg/kg PM2.5 group, ^dp < 0.05.