Table 3.
Subgroup analysis of the association between serum 25(OH)D levels and the stroke risk based on race.
| Race | N (%) | Model 1 OR (95% CI) |
P | Model 2 OR (95% CI) |
P | Model 3 OR (95% CI) |
P |
|---|---|---|---|---|---|---|---|
| Mexican Americans | |||||||
| 25(OH)D, nmol/L | |||||||
| Deficiency (<30) | 115 (7.75) | 0.762 (0.230-2.524) | 0.643 | 1.015 (0.310-3.320) | 0.979 | 0.868 (0.282-2.671) | 0.798 |
| Insufficiency (30-50) | 524 (34.98) | 0.676 (0.308-1.484) | 0.309 | 0.786 (0.364-1.697) | 0.522 | 0.778 (0.351-1.727) | 0.520 |
| Normal (50-125) | 878 (57.17) | Ref | Ref | Ref | |||
| Adequacy (≥125) | 2 (0.10) | - | - | - | |||
| Non-Hispanic whites | |||||||
| 25(OH)D, nmol/L | |||||||
| Deficiency (<30) | 108 (10.62) | 4.651 (1.908-11.338) | <0.001 | 3.087 (1.390-6.856) | 0.004 | 2.501 (1.094-5.720) | 0.024 |
| Insufficiency (30-50) | 353 (29.13) | 1.957 (1.257-3.047) | 0.002 | 1.982 (1.246-3.153) | 0.003 | 1.853 (1.170-2.934) | 0.006 |
| Normal (50-125) | 731 (59.69) | Ref | Ref | Ref | |||
| Adequacy (≥125) | 7 (0.56) | 0.954 (0.456-1.995) | 0.897 | 0.922 (0.481-1.767) | 0.800 | 1.011 (0.574-1.781) | 0.969 |
| Non-Hispanic blacks | |||||||
| 25(OH)D, nmol/L | |||||||
| Deficiency (<30) | 123 (2.40) | 0.746 (0.437-1.273) | 0.262 | 1.009 (0.550-1.851) | 0.976 | 0.837 (0.470-1.492) | 0.528 |
| Insufficiency (30-50) | 567 (12.43) | 0.555 (0.209-1.473) | 0.218 | 0.739 (0.276-1.977) | 0.529 | 0.702 (0.264-1.864) | 0.459 |
| Normal (50-125) | 3461 (81.65) | Ref | Ref | Ref | |||
| Adequacy (≥125) | 143 (3.53) | 1.739 (0.185-16.329) | 0.613 | 0.819 (0.097-6.899) | 0.848 | 1.298 (0.145-11.605) | 0.808 |
| Other races | |||||||
| 25(OH)D, nmol/L | |||||||
| Deficiency (<30) | 403 (27.69) | 0.615 (0.135-2.798) | 0.513 | 1.050 (0.298-3.695) | 0.937 | 0.828 (0.267-2.571) | 0.734 |
| Insufficiency (30-50) | 582 (39.36) | 0.334 (0.089-1.261) | 0.092 | 0.408 (0.107-1.555) | 0.172 | 0.379 (0.095-1.502) | 0.151 |
| Normal (50-125) | 515 (32.36) | Ref | Ref | Ref | |||
| Adequacy (≥125) | 11 (0.60) | - | - | - |
Notes: model 1 is the univariate logistic regression analysis for 25(OH)D levels; model 2 is the multivariate logistic regression analysis after adjustments for age and gender; model 3 is the multivariate logistic regression analysis after adjustment for the covariates including age, gender, BMI, educational level, hypertension, vitamin B, and CRP levels.