Table 3:
Efficacy Parameter | DESTINY-Breast01 HER2-positive Breast Cancer 5.4mg/kg (N = 184) |
---|---|
Confirmed Objective Response Rate (95% CI) | 60.3% (52.9, 67.4) |
Complete Response | 4.3% |
Partial Response | 56% |
Duration of Response* Median, months (95% CI)** | 14.8 (13.8, 16.9) |
ORR 95% CI calculated using Clopper-Pearson method
DOR is based on median duration of follow-up of 11.1 months.
Median DOR based on Kaplan-Meier estimate; 95% CI calculated using Brookmeyer-Crowley method