Fig. 2.

GEF regulates expression of proteins relevant to sarcopenia in old mice. Expression levels of proteins involved in muscle protein synthesis (MyoD and MEF-2) or degradation (Fbx32 and MuRF1) was measured in (A) the GAS and (B) the QUA muscle by western blotting. GAPDH served as a control. (C) IGF-1 levels in serum. Statistical significance was decided using one-way ANOVA, followed by Tukey's post-hoc test. Values with different letters are significantly different; p < 0.05 (a > b > c > d).