Table 4.
Area under the curve (AUC), cut-off value, sensitivity and specificity of plasma miR-155 and other parameters in COVID-19 patients
| miR-155 | Ferritin | CRP | D-dimer | |
|---|---|---|---|---|
| (A) For the detection of COVID-19 disease | ||||
| AUC | 0.986 | 0.893 | 1 | 1 |
| Cut-off value | 1.81 | 134.8 | 9.1 | 0.09 |
| Asymptotic significance | 0.000a | 0.000a | 0.000a | 0.000a |
| Sensitivity | 90% | 84% | 100% | 100% |
| Specificity | 100% | 85% | 100% | 100% |
| (B) For the detection of COVID-19 disease severity | ||||
| AUC | 0.75 | 0.86 | 0.54 | 0.78 |
| Cut-off value | 2.88 | 286.5 | 71.8 | 0.65 |
| Asymptotic significance | 0.000a | 0.000a | 0.45 | 0.000a |
| Sensitivity | 76% | 81% | 57% | 69% |
| Specificity | 76% | 82% | 53% | 79% |
AUC, area under the curve.
aHighly significant at p value <0.001.