TABLE 1.
Tissue urea concentrations in PDD cases and controls.
| Region | Controls (n = 9) (mmol/kg) | PDD cases (n = 9) (mmol/kg) | Fold-change | P-Value |
| CB | 9.6 (2.7–16.4) | 35.2 (15.4–55.0) | 3.7 | 0.003 |
| MCX | 9.2 (2.5–16.0) | 37.7 (15.7–59.7) | 4.1 | 0.002 |
| PVC | 8.1 (2.3–13.9) | 34.9 (14.6–55.2) | 4.3 | 0.001 |
| HP | 9.0 (2.6–15.4) | 37.6 (10.7–64.4) | 4.2 | 0.004 |
| SN | 11.6 (3.4–19.9) | 45.8 (17.3–74.2) | 3.9 | 0.006 |
| MTG | 11.0 (2.3–19.6) | 46.9 (17.9–76.0) | 4.3 | 0.002 |
| MED | 8.5 (2.3–14.7) | 38.9 (14.9–62.9) | 4.6 | 0.002 |
| CG | 8.8 (3.0–14.6) | 48.4 (17.6–79.1) | 5.5 | 0.0008 |
| PONS | 8.8 (2.2–15.5) | 34.2 (15.4–53.0) | 3.9 | 0.003 |
Mean tissue-urea concentrations ± 95% confidence intervals expressed in mmol/kg. Significance of case-control differences was determined using the Mann-Whitney-U test wherein P < 0.05 has been considered significant. Fold-changes are cases compared to controls.
Bolded values show significant case-control differences.