Table 1.

Multiple liver phosphatidylethanolamine concentrations differ in male vs female livers and are increased by CerS6 KO. Red, p<0.05; pink, p<0.1; green, p<0.05; light geen, p<0.1.

		Anova contrasts
		Female			Male			$\frac{\mathrm{Female}}{\mathrm{Male}}$
		$\frac{\mathrm{KO}}{\mathrm{WT}}$			$\frac{\mathrm{KO}}{\mathrm{WT}}$			WT			KO
Sub Pathway	Metabolites	FD	CTRL	FS	FD	CTRL	FS	FD	CTRL	FS	FD	CTRL	FS
Phosphatidylethanolamine (PE)	1,2-dipalmitoyl-GPE (16:0/16:0)*	1.37	1.17	1.54	1.45	1.09	1.12	1.30	1.30	1.25	1.23	1.40	1.72
	1-palmitoyl-2-stearoyl-GPE (16:0/18:0)*	1.58	0.76	1.38	1.99	0.76	0.63	2.86	3.32	2.04	2.27	3.33	4.44
	1-palmitoyl-2-oleoyl-GPE (16:0/18:1)	1.29	1.15	1.56	1.51	1.32	1.22	0.91	0.71	0.78	0.78	0.61	0.99
	1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)	1.19	1.62	1.67	1.53	1.80	1.66	0.66	0.53	0.61	0.52	0.47	0.61
	1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)*	1.03	1.11	1.17	1.12	1.14	1.12	0.83	0.77	0.81	0.76	0.75	0.85
	1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)*	1.00	1.07	1.05	1.08	1.14	0.96	1.24	1.19	1.07	1.14	1.12	1.18
	1-stearoyl-2-oleoyl-GPE (18:0/18:1)	1.19	1.00	1.32	1.37	1.17	1.08	1.14	0.94	1.02	0.99	0.80	1.24
	1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*	1.04	1.17	1.42	1.32	1.55	1.40	0.97	0.90	0.91	0.76	0.67	0.92
	1-stearoyl-2-arachidonoyl-GPE (18:0/20:4)	0.98	0.98	1.08	1.07	1.09	1.02	1.01	1.02	0.93	0.93	0.92	0.99
	1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)*	0.96	1.08	1.04	1.18	1.36	0.98	1.50	1.41	1.08	1.22	1.13	1.16
	1-oleayl-2-linoleoyl-GPE (18:1/18:2)*	1.22	1.30	1.57	1.39	1.38	1.53	0.65	0.52	0.68	0.57	0.49	0.69
	1-oleoyl-2-arachidonoyl-GPE (18:1/20:4)*	1.08	0.99	1.10	1.14	1.01	0.99	1.01	0.85	0.89	0.95	0.83	0.99
	1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6)*	1.04	0.96	0.98	1.07	1.02	0.87	1.19	1.07	1.04	1.16	1.01	1.18
	1,2-dilinoleoyl-GPE (18:2/18:2)*	0.98	1.29	1.63	1.63	2.25	2.20	0.59	0.58	0.73	0.35	0.33	0.54
	1-linoleoyl-2-arachidonoyl-GPE (18:2/20:4)*	1.02	1.00	1.27	1.27	1.39	1.37	0.74	0.74	0.83	0.60	0.53	0.77