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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Gut. 2021 May 6;70(12):2330–2336. doi: 10.1136/gutjnl-2020-323450

Table 3.

Sugar-sweetened beverage intake at age 13–18 and risk of early-onset colorectal cancer

<1 serving/wk 1 serving/wk to <2 servings/d ≥2 servings/d Ptrenda Each serving/d increase
Person-years 113 475 218 172 25 788
No. of cases 12 17 6
Age- and energy-adjusted RR (95% CI) 1 [Reference] 0.73 (0.34–1.58) 2.43 (0.83–7.05) 0.05 1.19 (0.92–1.54)
Multivariable RR (95% CI)b 1 [Reference] 0.78 (0.36–1.73) 3.41 (1.08–10.8) 0.01 1.32 (1.00–1.75)

Abbreviations: CI, confidence interval; RR, relative risk.

One beverage serving is 8 oz.

a

Calculated using the median of each category of beverage intake as a continuous variable.

b

Additionally adjusted for race (white, nonwhite), height (continuous), body mass index at age 18 (continuous), pack-years of smoking before age 20 (continuous), intake of alcohol at age 15–17, red and processed meat, dietary fiber, total folate [from foods and supplements], and total calcium at age 13–18 (all continuous), multivitamin use at age 13–18 (yes, no), and physical activity at grade 9–12 (continuous).