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. 2021 May 11;70(12):3669–3677. doi: 10.1007/s00262-021-02955-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Specific ectopic ACTH expression was detected in the tumor specimens, in which case revealed anti-POMC antibody. Staining and immunohistochemistry for ACTH in the tumor tissues. Tumor specimen in the cases #2 and #14 specifically demonstrated ectopic ACTH expression. In contrast, tumor specimen in other cases was negative for ACTH. The representative results from a part of patients without anti-POMC antibody are shown. Scale bars: 200 µm