Table 1.
Patients’ characteristics at baseline
| Overall n = 29 | Responder n = 13 | Non-Responder n = 16 | P value | |
|---|---|---|---|---|
| Age, years | 54 (± 15.6) | 58 (± 11.7) | 43 (± 19.8) | 0.137 |
| Women, n [%] | 20 [69] | 10 [67] | 10 [71] | 1.000 |
| Body Mass Index, kg/m2 | 27 (± 6.5) | 30.8 (± 5.4) | 25 (± 6.2) | 0.558 |
| MADRS | 33 (± 8.7) | 39 (± 4.4) | 34 (± 7.8) | 0.314 |
| BDI-II | 36 (± 11.3) | 46.0 (± 9.7) | 38 (± 8.0) | 0.199 |
| Duration of current depressive episode, weeks | 28 (± 20.1) | 19.8 (± 13.0) | 29.3 (± 24.7) | 0.226 |
| Age at initial diagnosis, years | 32 (± 15.6) | 30 (± 8.1) | 37 (± 23.8) | 0.938 |
| History of suicide attempt, n [%] | 9 [31] | 3 [20] | 6 [43] | 0.245 |
| Antidepressants, n [%] | 17 [59] | 10 [67] | 7 [50] | 0.462 |
| Atypical antipsychotics, n [%] | 13 [44.8] | 8 [53] | 5 [36] | 0.462 |
| Norepinephrine, ng/l | 35 (± 19.8) | 39.3 (± 35.7) | 32.8 (± 10.8) | 0.678 |
| Epinephrine, ng/l | 36 (± 18.8) | 45.3 (± 33.1) | 28.8 (± 11.4) | 0.793 |
| Cortisol, µg/dl | 14 (± 6.2) | 14.8 (± 1.6) | 12.7 (± 5.5) | 0.295 |
Patients’ characteristics presented as mean ± standard deviation (SD) or absolute quantity and percentual (n [%]); MADRS = Montgomery-Åsberg Depression Rating Scale, BDI-II = Beck Depression Inventory-II