Table 3.
Adverse events after first infusion of CAR-T cells
| Adverse event | Grade 1, % | Grade 2, % | Grade 3,% | Grade 4, % |
|---|---|---|---|---|
| Inflammation-related event | ||||
| Fever | 57.1 | 14.3 | ||
| Febrile neutropenia | 57.1 | |||
| Cytokine release syndrome | 71.4 | |||
| Hematological event | ||||
| Anemia | 28.6 | 28.6 | 7.1 | 7.1 |
| Leukopenia | 42.9 | 42.9 | 14.3 | |
| Neutropenia | 7.1 | 21.4 | 35.7 | 21.4 |
| Lymphopenia | 14.3 | 7.1 | 78.6 | |
| Thrombocytopenia | 35.7 | 7.1 | 7.1 | 7.1 |
| Fibrinogen decreased | 7.1 | 7.1 | ||
| Nervous system event | ||||
| Chemical laboratory abnormalities | ||||
| Alanine aminotransferase increased | 21.4 | |||
| Aspartate aminotransferase increased | 7.1 | |||
| Gamma glutamyl transpeptidase increased | 7.1 | |||
| Blood bilirubin increased | 7.1 | |||
| Serum creatinine increased |