Table 1.
Cellular sensitivity of trastuzumab and T-DM1.
| Cell line | Trastuzumab sensitivity | T-DM1 sensitivity (IC50 (µg/ml)) |
|---|---|---|
| SK-BR-3 | +++ | +++ (0.0058) |
| SKOV-3 | − | + (1.2) |
| AU-565 | +++ | +++ (0.0046) |
| HCC1954 | + | +++ (0.0065) |
| MDA-MB-435 | + | ++ (0.12) |
The table shows trastuzumab sensitivity (not sensitive (−), low sensitivity (+), high sensitivity (+++)), and T-DM1 sensitivity (IC50 average of three experiments) in the indicated cell lines. Graphic presentations of the viability data are found in Fig. 1. Source data provided.