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. 2021 Nov 5;11:21772. doi: 10.1038/s41598-021-01176-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of serum SERPINE1 antigen levels between the aCI and HDs groups. (a) Serum SERPINE1 antigen levels were examined using sandwich enzyme-linked immunosorbent assay in healthy donors and patients with acute cerebral infarction. The results are shown in a box-whisker plot. The p values were calculated using the Kruskal–Wallis test. (b) SERPINE1 antibody levels were plotted against SERPINE1 antigen levels in a scattered plot. The correlation coefficient (r value) and p value were calculated using the Pearson product–moment correlation coefficient.