Table 3.
Spearman correlation analysis between the serum SERPINE1 antibody levels and clinical features.
| Variable | Spearman rank correlation coefficient (r) | p value |
|---|---|---|
| Age | 0.2308 | < 0.0001 |
| Height | 0.0975 | 0.0037 |
| Weight | − 0.1306 | 0.0001 |
| BMI | − 0.0386 | 0.2562 |
| Right IMT | 0.2263 | < 0.0001 |
| Left IMT | 0.1974 | < 0.0001 |
| Maximum IMT | 0.2231 | < 0.0001 |
| AST | − 0.0319 | 0.4139 |
| ALT | 0.0178 | 0.6488 |
| ALP | 0.0684 | 0.0934 |
| LDH | − 0.0028 | 0.9442 |
| Tbil | − 0.0798 | 0.043 |
| CHE | − 0.0537 | 0.239 |
| γ-GTP | 0.071 | 0.0794 |
| TP | − 0.0502 | 0.2058 |
| ALB | − 0.1083 | 0.0059 |
| BUN | 0.034 | 0.3841 |
| Creatinine | 0.032 | 0.413 |
| eGFR | − 0.0509 | 0.214 |
| UA | 0.0014 | 0.9753 |
| AMY | 0.0018 | 0.9722 |
| T-CHO | − 0.0251 | 0.5509 |
| HDL-C | − 0.0077 | 0.878 |
| TG | − 0.042 | 0.3827 |
| Na | 0.0491 | 0.2124 |
| K | − 0.0461 | 0.2417 |
| Cl | 0.0689 | 0.0801 |
| CRP | 0.0486 | 0.3003 |
| WBC | 0.1075 | 0.0058 |
| RBC | − 0.0962 | 0.0136 |
| HGB | − 0.0741 | 0.0575 |
| HCT | − 0.0762 | 0.0509 |
| PLT | − 0.0045 | 0.9075 |
| Blood glucose | 0.0804 | 0.0482 |
| HbA1c | 0.0304 | 0.5008 |
| Smoking period | 0.0372 | 0.3433 |
| Alcohol frequency | − 0.0402 | 0.326 |
A correlation analysis was performed to identify the relationship between SERPINE 1 antibody levels and the clinical features of the validation cohort.
Correlation coefficient (r) and p values were calculated using Spearman correlation analysis. Significant correlations are marked in bold.
BMI body mass index, IMT intima-media thickness, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, LDH lactate dehydrogenase, Tbil total bilirubin, CHE choline esterase, γ-GTP gamma-glutamyl transpeptidase, TP total protein, ALB albumin, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, UA uric acid, AMY amylase, T-CHO total cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglyceride, CRP C-reactive protein, WBC white blood cell count, RBC red blood cell count, HCT hematocrit, PLT platelet count, HbA1c hemoglobin A1c.