Table 6.

Positive predictive value including the factors associated with the prediction of acute cerebral infarction.

	Clinical risk factors				Clinical risk factors +
					Anti-SERPINE1-Ab ≥ 1857
	aCI	HD	PPV (%)	Specificity (%)	aCI	HD	PPV (%)	Specificity (%)
Age ≥ 60 years	408	79	83.8	71.8	252	30	89.4	89.3
HT	331	57	85.3	79.7	200	27	88.1	90.4
DM	123	10	92.5	96.4	73	3	96.1	98.9
Age ≥ 60 years + HT	301	28	91.5	90.0	188	12	94.0	95.7
Age ≥ 60 years + DM	107	4	96.4	98.5	68	1	98.6	99.6
Age ≥ 60 years + HT + DM	89	2	97.8	99.3	58	0	100.0	100.0

Results of the multivariate analysis were used to determine the positive predictive value based on the clinical factors that were particularly relevant.

The numbers under aCI and HD indicate the number of participants.

The left side of the table shows the number of people with only clinical risk factors, whereas the right side shows the number of people with clinical risk factors and anti-SERPINE1 antibody levels above the cutoff value.

The total number of aCI and HD were 459 and 281, respectively.

HT hypertension, DM diabetes mellitus, disease, aCI acute cerebral infarction, HD healthy donor, PPV positive predictive value, Ab antibody.