. 2021 Nov 5;11:21738. doi: 10.1038/s41598-021-01101-z

Table 3.

Association between categorical thyroid function and TyG index.

Model^#	Variable	Total (n = 5727)				Male (n = 2882)				Female (n = 2845)
Model^#	Variable	Beta	95% CI		P value	Beta	95% CI		P value	Beta	95% CI		P value
1					< 0.0001*				0.004*				< 0.0001*
	Overt hypothyroidism	0.194	0.081	0.308	0.001	0.156	− 0.092	0.404	0.216	0.263	0.136	0.391	< 0.0001
	Subclinical hypothyroidism	0.024	− 0.028	0.076	0.365	− 0.034	− 0.120	0.051	0.427	0.096	0.033	0.159	0.003
	Euthyroid	0 (ref)				0 (ref)				0 (ref)
	Subclinical hyperthyroidism	− 0.008	− 0.063	0.047	0.788	0.046	− 0.029	0.121	0.231	− 0.056	− 0.127	0.015	0.120
	Overt hyperthyroidism	− 0.147	− 0.232	− 0.062	0.001	− 0.223	− 0.351	− 0.095	0.001	− 0.066	− 0.175	0.043	0.234
2					< 0.0001*				0.238				< 0.0001*
	Overt hypothyroidism	0.127	0.036	0.217	0.006	0.012	− 0.220	0.244	0.919	0.166	0.075	0.257	< 0.0001
	Subclinical hypothyroidism	0.048	− 0.003	0.100	0.066	0.018	− 0.077	0.112	0.715	0.067	0.010	0.125	0.022
	Euthyroid	0 (ref)				0 (ref)				0 (ref)
	Subclinical hyperthyroidism	− 0.024	− 0.072	0.024	0.330	− 0.011	− 0.078	0.056	0.748	− 0.043	− 0.110	0.023	0.201
	Overt hyperthyroidism	− 0.093	− 0.159	− 0.027	0.006	− 0.151	− 0.280	− 0.022	0.022	− 0.071	− 0.145	0.003	0.060
3					0.001*				0.320				< 0.0001*
	Overt hypothyroidism	0.121	0.031	0.211	0.009	0.006	− 0.233	0.245	0.961	0.160	0.073	0.247	< 0.0001
	Subclinical hypothyroidism	0.049	− 0.003	0.101	0.064	0.009	− 0.088	0.107	0.849	0.071	0.015	0.127	0.013
	Euthyroid	0 (ref)				0 (ref)				0 (ref)
	Subclinical hyperthyroidism	− 0.018	− 0.063	0.028	0.442	− 0.002	− 0.067	0.064	0.958	− 0.039	− 0.101	0.023	0.220
	Overt hyperthyroidism	− 0.086	− 0.152	− 0.020	0.011	− 0.159	− 0.304	− 0.014	0.032	− 0.059	− 0.124	0.006	0.077

^#Model 1: linear regression analysis, 2: multiple regression analysis after adjustment for age, sex, systolic blood pressure, BMI, alcohol consumption, 3: multiple regression analysis after adjustment for age, sex, systolic blood pressure, waist circumference, alcohol consumption *P-values < 0.05 were considered as statistically significant.