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. 2021 Aug 24;10(2):941–953. doi: 10.1007/s40120-021-00272-1

Table 2.

Annual transition probabilities by current health state and sample populations

Sample variant Annual probability of transitioning to a more severe dementia health state from current health state
Asymptomatic MCI-AD Mild AD dementia Moderate AD dementia Severe AD dementiaa
Incident population 40.8% 26.5% 45.2% 59.8% 46.7%
Prevalent population 23.4% 36.9% 43.4% 55.5% 41.6%

AD Alzheimer’s disease, MCI-AD mild cognitive impairment due to Alzheimer’s disease

aTransition from severe AD dementia to death