Table 4.

Annual transition probabilities among the prevalent population with amyloid restriction

Initial state	Next state
	Asymptomatic	MCI-AD	Mild AD dementia	Moderate AD dementia	Severe AD dementia	Died
Asymptomatic	76.6%	21.8%	0.7%	0.0%	0.0%	0.9%
MCI-AD	2.2%	60.9%	30.7%	3.7%	0.6%	1.9%
Mild AD dementia	0.0%	2.6%	54.0%	33.6%	4.3%	5.6%
Moderate AD dementia	0.0%	0.0%	3.0%	41.5%	30.2%	25.3%
Severe AD dementia	0.0%	0.0%	0.0%	0.9%	57.5%	41.6%

AD Alzheimer’s disease, MCI-AD mild cognitive impairment due to Alzheimer’s disease

Please see Table S2 in the electronic supplementary materials for counts of observed transitions and unique patients by initial state among the prevalent population with amyloid restriction