Figure 1.

Igls criteria in a clinical setting on a population level. Illustration of the Igls criteria utility for cross-sectional comparison between β-cell replacement modalities, illustrated by consecutive data from center A at 0.5, 1, 2, and 4 years posttransplantation. Igls criteria functional categories are presented as a percentage of each population for islet transplantation (ITx; n = 36), solitary pancreas transplantation (PTx; n = 29), and SPK (n = 23), respectively. Describing the natural course posttransplantation according to current clinical practice, this includes 17 islet transplant recipients that received a subsequent islet infusion by the 2-year assessment, and 1 pancreas transplant recipient with a failed graft at 1 and 2 years receiving a subsequent whole pancreas transplant with optimal graft function at 4 years. SPK, simultaneous pancreas-kidney transplantation.