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Summary of significant neuroanatomical effects
| Sex | Male | Female | ||
|---|---|---|---|---|
| Endpoint | FM 550 | 5MT | FM 550 | 5MT |
| OT | — | ↑ OT-ir neurons in SON (5MT) | — | — |
| AVP | — | — | ↓ AVP-ir neurons in medial PVN (1000 µg) ↓ AVP-ir neurons in anterior/medial PVN (2000 µg) |
↑ AVP-ir neurons in posterior PVN (5MT) |
| TH | ↓ TH-ir A13 neurons in ZI (1000ug) | — | ↑ TH-ir A13 neurons in ZI (500 µg) | ↑ TH-ir A13 neurons in ZI (5MT) |
