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Presence of rare PDGFRA‐amplified tumor cells in initial biopsy material. Analysis of the initial biopsy confirms mutually exclusive rare tumor cells with PDGFRA amplification (bottom, middle) among more numerous NTRK2‐rearranged tumor cells (bottom left, right). White signal: PDGFRA‐specific probe; green and red signals: NTRK2 break‐apart probes. Abbreviations: NTRK, neurotrophic receptor tyrosine kinase; PDGFRA, platelet‐derived growth factor receptor alpha.
