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. 2021 Jun 14;106(10):e3946–e3956. doi: 10.1210/clinem/dgab416

Figure 2.

Figure 2.

Determination of reference intervals of SHBG in men and women. Weighted data distribution of SHBG in the sub-cohort of “healthy” men (A) (n = 815, unweighted number) and women (B) (n = 662, unweighted number) and weighted data distribution of natural log-transformed SHBG (Ln SHBG) in the “healthy” men (C) and women (D). After truncation of Ln SHBG values, which were outside of mean ± 3 SD, mean ± 2 SD of Ln SHBG was calculated in the “healthy” men (E) (n = 814, unweighted number) and women (F) (n = 661, unweighted number). The resulting reference interval of SHBG in men was 12.6 to 92.4 nmol/L, and it was 18.4 to 211.5 nmol/L in women. Abbreviation: SHBG, sex hormone-binding globulin.